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Local Anesthesia Powders

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Ropivacaine Mesylate (S-Ropivacaine Mesylate) Powder CAS 854056-07-8

 

Product name: Ropivacaine mesylate
Synonyms: (S) -Ropivacaine Mesilate; S-Ropivacaine mesylate
CAS: 854056-07-8
Formula: C18H30N2O4S
MW: 370.5068
Appearance White crystalline powder
Assay 99.5%

 

Ropivacaine Mesylate Description:

 

Ropivacaine Mesylate is a new long-acting amide local anesthetic, as a pure isomer, with anesthesia and analgesic dual role, high concentration can produce surgical anesthesia, low concentration can effectively block the sensory nerve conduction and motor nerve. Its pharmacological properties for cardiac toxicity is low, sensory block separation is more obvious, there is vasoconstriction, so no need to add adrenaline. Clinical mainly for surgical anesthesia, local anesthesia and acute pain control.

 

Ropivacaine Mesylate Applications:

 

Ropivacaine Mesylate for topical anesthesia, including infants infants aged 12 years or older, with nerve block, epidural and intrathecal anesthesia. It also represents 1 to 12 years old pain in children with peripheral nerve block and tail epidural pain. It is also sometimes used for surgical pain in children with anesthesia.

Ropivacaine Mesylate is usually combined with fentanyl for epidural analgesia, such as pregnant women, bupivacaine, usually intravenous liposomes, which are effective for treating animals. The experiment was secondary to local anesthetic overdose of severe cardiotoxicity in humans called Lipid Rescue.

 

Ropivacaine Mesylate COA:

 

Items Specification Results
Description White or practically white crystalline powder White crystalline powder
Specific Rotation 30°~-35° 32°
Melting Range 232~239°C, and melting range is not more then 4°C 234~238°C
identification It complies with the test for specific optical rotation and melting point Conforms
Infrared absorption spectrophotometry should be consistent with levonorgestrel CRS Conforms
Loss on drying ≤0.5% 0.20%
Residue on ignition ≤0.3% 0.07%
Limit of Ethynyl Group 7.81%~8.18% 7.92%
Related substances Single impurity ≤0.5% single impurity<0.5%
Total Impurities ≤2.0% Total impurities<2.0%
Organic Volatile impurties Ethanol ≤5000ppm 1200ppm
Assay The product complies with specification in USP34
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