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Local Anesthesia Powders

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  • Specifications

 

Ropivacaine Hydrochloride (Ropivacaine HCL) Powder CAS 98717-15-8

 

Product Name Ropivacaine HCl
CAS NO. 132112-35-7
EINECS 205-248-5
Molecular Formula C15H25ClN2O2
Molecular Weight 328.88
Purity 99%
Grade Pharmaceutical Grade
Appearance White crystalline powder
Usage Anesthetic
Origin China

 

Ropivacaine Hydrochloride Description:

 

Ropivacaine is an anesthetic (numbing medicine) that blocks the nerve impulses that send pain signals to your brain. Ropivacaine is used as a local (in only one area) anesthesia for a spinal block, also called an epidural. The medication is used to provide anesthesia during a surgery or C-section, or to ease labor pains.Ropivacaine is a local anaesthetic drug belonging to the amino amide group. The name ropivacaine refers to both the racemate and the marketed S-enantiomer. Ropivacaine may also be used for purposes not listed in this medication guide. Ropivacaine is indicated for local anaesthesia including infiltration, nerve block, epidural and intrathecal anaesthesia in adults and children over 12 years. It is also indicated for peripheral nerve block and caudal epidural in children 1-12 years for surgical pain. It is also sometimes used for infiltration anaesthesia for surgical pain in children.

Ropivacaine is often coadministered for epidural analgesia, for example in pregnant women during labour.

 

Ropivacaine Hydrochloride Application:

 

(1) Surgical anesthesia: Epidural anesthesia (including epidural anesthesia during cesarean section); Local infiltration anesthesia.

(2) Acute pain control: For postoperative or labor analgesia continuous epidural infusion can be used can also be intermittent medication; Local infiltration anesthesia.

 

Pharmacological effects:

 

Since the discovery of long-acting local anesthetic can induce cardiac arrest, people have been looking for less fat-soluble, more safe alternative drugs. Ropivacaine is such a new long-acting amide local anesthetic, its role for a long time, and has anesthesia and analgesic effect. Its pharmacological characteristics for the heart toxicity is low, sensory block and movement block separation is obvious, with peripheral vasoconstriction. So the drug is particularly suitable for postoperative analgesia and obstetric anesthesia.

 

Ropivacaine has the following advantages compared with traditional local anesthetic:

 

1, the effect of the role of ropivacaine significantly longer than other long-acting local anesthetic, subcutaneous infiltration of anesthesia more than the same concentration of bupivacaine 2 to 3 times longer.

2, the efficacy of unique – ropivacaine feeling – movement block separation is much greater than bupivacaine, and a higher clearance rate, making it more suitable for analgesic.

3, controllability – ropivacaine anesthetic effect in a dose-dependent, that is, ropivacaine produced by the degree of sensory and motor block can be predictable and controllable.

4, low side effects – ropivacaine is not the general long-term local anesthetic heart toxicity of the larger shortcomings, the goods rarely occur cardiotoxicity, and the fetus on the goods with good tolerance.

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