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    MK-2866 (Ostarine/Enobosarm) SARM Powder (841205-47-8)

     

    MK-2866 ( Ostarine )
    CAS:841205-47-8
    Molecular Formula: C19H14F3N3O3
    Molecular Weight: 389.33
    Appearance: White fine powder
    Product specification: 99%
    Package: Foil bags
    Storage: Store in a cool, dry place and keep away from direct strong light.
    Alias: ((2R)-3-(4-cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide); GTx-024; MK-2866; (S)-N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide; Ostarine (MK-2866)

     

    MK-2866 (MK-2866) Description:

     

    Ostarine, also known as MK-2866 is a SARM (selective androgen receptor module) created by GTx to avoid and treat muscle wasting. It can later on be a cure for avoiding atrophy (total wasting away of a body part), cachexia, sarcopenia and Hormone or Testosterone Replacement Therapy.

    Ostarine belongs to a class of chemicals know as SARMS or selective androgen receptor modulators. SARMS create selective anabolic activity at certain androgen receptors. In comparison to testosterone and other anabolic steroids, the advantage of SARMS, is they do not have androgenic activity in non-skeletal muscle tissues. Ostarine is effective in maintaining and increasing lean body mass.

     

    MK-2866 (MK-2866) Application:

     

    Ostarine is a potent and tissue-selective androgen receptor modulator (SARM) for treatment of conditions such as muscle wasting and osteoporosis. These patent products for research purposes only use. Ostarine is an orally bioavailable nonsteroidal selective androgen receptor modulator. Therefore, ostarine can be used for treatment of conditions such as muscle wasting and osteoporosis.

     

    Benefits of MK-2866 (MK-2866) :

     

    1. Lean muscle gain(bulking)

     

    Ostarine is the most anabolic of any SARMS, making its first and foremost use for wanting to gain lean muscle. The gains in total weight will not be comparable to bulking steroids, however the total gains will almost entirely be lean muscle.
    The gains that are made on ostarine are very keepable and users generally see an increase of up to 7 lbs. of lean body mass over and 8 week cycle at 25mg day (diet dependent). The most common dosage is 25 mg for 8 weeks. The side effects that one encounters with steroid use will not be present on cycle.
    Generally, with ostarine, the higher the dosage, the more suppression. Although suppression is minimal and is nowhere comparable to suppression that one encounters on steroids, any cycle of ostarine over a 4 weeks period requires a 3 week mini pct. A serm is not required in this pct.

     

    2. Losing Bodyfat (cutting)

     

    Ostarine would primarily fit into a cutting protocol for the maintenance of muscle mass while reducing calories. One of the most disheartening outcomes of cutting is the loss hard earned muscle mass. The drop in metabolic rate and hormone levels (T3, IGF, Testosterone etc) with the lack of calories is a perfect catabolic environment for loss of muscle tissue. As Ostarine has anabolic effects, the dieter can cut calories without having to worry about muscle or strength loss. Ostarine has also shown noticeable nutrient partitioning effects among users, another reason why it can be of great help when cutting.
    A 15-20 mg dosing protocol for 6-8 weeks is good for cutting with Ostarine without undergoing any side effects or high suppression. However it must be stated that due to the lack of androgenicity, muscle hardness and overall results are not as prominent as with the SARM S-4.

     

    Advantages of Ostarine (MK-2866) when compared to steroids:

     

    It is non methylated so it is non toxic to the liver or blood pressure
    Some suppression may be present at doses of 25mg+ run for longer than 4 weeks, however a stringent PCT of prescription SERMs like Nolvadex or Clomid is not necessary.
    High oral bioavailability without significant damage to your liver as with oral steroids.
    Great sense of well being while on, (without the aggression which can often detrimentally impact users daily lives).
    No need for a long time period off between cycles; the recommended time of period for normal steroid cycles would be Time on + PCT, so for a typical 6 week cycle and 4 week PCT, a user would have to wait another 10 weeks after PCT to start another cycle where SARMS recovery requires minimal rest in between.
    Ostarine also resulted in a dose-dependent decrease in LDL and HDL cholesterol levels, with the average LDL/HDL ratio for all doses remaining in the low cardiovascular risk category – hence there is little impact on cholesterol values

     

    COA of MK-2866 (MK-2866):

     

    Item Specification Result
    Appearance An odorless, almost white or white powder pass
    Identificaton The retention time of the major peak is
    confirm to the RS
    pass
    Loss on Drying Not more than 0.5% 0.33%
    Assay(HPLC) Not less than 99.0% 99.59%
    Ignition residue Not more than 0.1% pass
    Heavy metal Not more than 20 ppm pass

     

    Side Effects of MK-2866 (MK-2866):

     

    The side effects of MK 2866 are limited as it appears to be a relatively side effect friendly drug. Many of the adverse effects associated with anabolic steroids will not exist with this SARM; however, some will, although mildly.

    Estrogenic: The side effects of MK 2866 should not include those of an estrogenic nature as the SARM does not aromatize. There is no conversion of testosterone to estrogen associated with this drug. Water retention, bloating, gynecomastia or high blood pressure due to water retention cannot occur. However, data shows that some increases in existing estrogen may occur, but should be very mild and not enough to warrant the use of an anti-estrogen. If this very slight increase is concerning, if an anti-estrogen is used, you may easily bottom out your estrogen levels, which can lead to numerous hormone imbalances and related effects.

    Androgenic: Androgenic side effects of MK 2866, despite directly affecting the androgen receptor should not exist. This compound does not convert to DHT; acne and hair loss cannot occur. Androgenic side effects associated with virilization in women are also impossible. As there is no direct androgenic activity related to DHT, prostate issues should also be non-existent.

    Cardiovascular: The side effects of MK 2866 should present minimal cardiovascular risk. Both HDL and LDL levels may be reduced, but all data shows minimal to insignificant reductions.

    Testosterone Suppression: It’s often said SARM’s will not suppress natural testosterone production, and it’s true they will not compared to anabolic steroids. However, some suppression is possible, but complete suppression is not. A testosterone-boosting supplement may be warranted while using MK 2866. Post Cycle Therapy (PCT) data is somewhat inconclusive as to if this is needed. Some men seem to experience greater levels of testosterone suppression than others.

    Hepatotoxicity: Although orally administered, the side effects of MK 2866 do not include liver toxicity. MK 2866 does not belong to the C17-alpha alkylated (C17-aa) class of drugs like many oral anabolic steroids. It does not mirror the MI metabolite associated with the SARM S4 that gives that particular SARM some hepatic activity.

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