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Anti-Estrogen Powders

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  • Specifications

 

Exemestane (Aromasin) Powder (107868-30-4)

 

Alias: Exemestan, Aromasin.
CAS ID: 107868-30-4
MF: C20H24O2
MW: 296.4
Aromasin Purity: 99.18%
Melting point: 155.13°C
Appearance: white solid powder.

 

Exemestane (Aromasin) Description:

 

Exemestane (trade name Aromasin) is a drug used to treat breast cancer. It is a member of the class of drugs known as aromatase inhibitors. Some breast cancers require estrogen to grow.

Those cancers have estrogen receptors (ERs), and are called ER-positive. They may also be called estrogen-responsive, hormonally-responsive, or hormone-receptor-positive. Aromatase is an enzyme that synthesizes estrogen.

Aromatase inhibitors block the synthesis of estrogen. This lowers the estrogen level, and slows the growth of cancers.

 

Exemestane (Aromasin) Function:

 

Treating advanced breast cancer in women who are past menopause and whose disease has progressed after treatment with other medicines.

It is also used in the treatment of early breast cancer in certain women who are past menopause and after treatment with other medicines. It may also be used for other conditions as determined by your doctor.

Exemestane is an aromatase inhibitor. It works by stopping the production of estrogen, which may decrease the size and growth of the tumor.

 

Exemestane (Aromasin) Usage:

 

Use exemestane as directed by your doctor.

Check the label on the medicine for exact dosing instructions. Check the label on the medicine for exact dosing instructions.

1. An extra patient leaflet is available with exemestane. Talk to your pharmacist if you have questions about this information.

2.Take exemestane by mouth after a meal at the same time every day.

3.Continue to take exemestane even if you feel well. Do not miss any doses.

4.If you miss a dose of exemestane, take it as soon as possible.If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

5.Ask your health care provider any questions you may have about how to use exemestane.

 

Exemestane (Aromasin) Dosage:

 

In a therapeutic setting to treat breast cancer, Aromasin is only used after Nolvadex has failed. This is normally after 2-3 years of Nolvadex therapy. From here Aromasin is given to the patient at a dose of 25mg per day, which will normally last another 2-3 years or until the cancer’s progression has come to a halt. This is normally followed by more Nolvadex therapy in an effort to halt the cancer from returning. This is a highly successful plan in the fight against breast cancer.

In a performance setting, standard Aromasin doses will normally be 12.5-25mg every other day. Most should be fine with 12.5mg every other day, with some getting by with only two to three doses per week. The individual’s total sensitivity and the composition of the steroid in cycle in question will dictate the final outcome. There will be, however, some who require a daily dose with as much as 25mg per day.

 

Exemestane (Aromasin) COA:

 

TEST ITEMS SPECIFICATION RESULTS
Description : White Crystalline Powder White Powder
Identification : Positive Positive
Assay(by HPLC) : 98.0~102.0% 98.64%
Absorbance(E1cm) : 465~495 482.5
Melting Point : 191~195°C 193.5~195.0°C
Loss On Drying : 0.5%max 0.19%
Specific Rotation : +288°~ +298° +290.2°
Residue On Ignition : 0.1%max 0.03%
Related Substances : Total:1.5%max <1.3%
Single:0.5%max <0.4%
Residue Solvents : 0.2%max 0.10%
Heavy Metals : 20PPm max <10PPm
Conclusion The specification conform with enterprise standard.

 

Exemestane (Aromasin) HPLC:

 

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