Letrozole (Femara) Raw Powder (112809-51-5)
Product Name:Letrozole
CAS : 112809-51-5
Synonyms:FEMARA;CGS-20267;LETROZOL;LETROZOLE;LetrozoleUsp28;Letrozole99%;CGS-20267, Femara
Purity:99%
Appearance:White or light yellow crystal
Molecular Formula: C17H11N5
Molecular Weight: 285.31
Package:1/foil bag
Usage: Used as API in Treatment of breast disease.
Letrozole (Femara) Description:
Letrozole lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body. Letrozole is an aromatase inhibitor. It works by reducing the total amount of estrogen produced primarily in the body. This helps to starve cancer cells by depriving them of estrogen.
Letrozole is used to treat breast cancer (such as hormone-receptor-positive breast cancer) in postmenopausal women. It is often given to women who have been taking tamoxifen (Nolvadex, Soltamox) for 5 years. Primarily treating certain kinds of breast cancer in women past menopause. It may also be used for other conditions as determined by your doctor.
Letrozole is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Letrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.
This medication may also be used to treat infertility in women.
Letrozole (Femara) Applications:
Letrozole is used treat early breast cancer in women who have experienced menopause and who have had other treatments, such as radiation or surgery to remove the tumor.It is in a class of medications called nonsteroidal aromatase inhibitors,and works by decreasing the amount of estrogen produced by the body.
Letrozole is a powerful aromatase Inhibitor that was developed to fight breast cancer. This can slow or stop the growth of some types of breast cancer cells that need estrogen to grow.For athletes and bodybuilders, it used to combat the estrogenic side effects of anabolic steroids water-retention, acne and gynocomastia.
Letrozole (Femara) COA:
Tests |
Specifications |
Results |
Appearance |
White or off-white crystaline powder |
White Crystalline powder |
Solubility |
Soluble in Chloroform; Soluble in ethanol when heated |
Conform |
ldentification |
(1)Maximum absorption in wavelength of 240 nm Minimum absorption in wavelength of 215 nm |
Conform Conform |
|
(2)Infrared spectrum should be in accordance the dominant peak of contrast |
In accordance with the dominant peak of contrast |
Melting points |
182ºC-184ºC |
182ºC |
Related substances |
≤0.5% |
0.3% |
Single impurity |
≤0.3% |
0.2% |
Loss on drying |
≤1.0% |
0.8% |
[Assay]C17H11N5 (On anhydrous basis) |
≥98.0% |
99.2% |
Conclusion |
Conforms Specifications of Enterprise Standard. |
Letrozole (Femara) Dosage:
Generally, a good starting dosage for letrozole is 0.25 to 1 milligram (mg), taken every other day.You can take the tablets before or after your meals. The precise dosage is really dependent on how you want to use Letrozole. if you simply need something to use on cycle, the dosage should be much more conservative.