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Local Anesthesia Powders

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Bupivacaine Hydrochloride (Bupivacaine HCL) Powder CAS 14252-80-3


Product name: Bupivacaine hydrochloride
CAS No.: 14252-80-3
EINECS No.: 241-917-8
MF: C18H31ClN2O2
MW: 342.9
Appearance: White crystal powder
Purity: 98.5%~101.5%
Ash: 0.1% max
Loss on dry: 0.1% max
Heavy Metal: 10ppm max


Bupivacaine Hydrochloride Description:


Bupivacaine Hydrochloride is 2-Piperidinecarboxamide, 1-butyl-N-(2, 6-dimethylphenyl)-, monohydrochloride, monohydrate, a white crystalline powder that is freely soluble in 95 percent ethanol, soluble in water, and slightly soluble in chloroform or acetone.

Bupivacaine Hydrochloride is available in sterile isotonic solutions with and without epinephrine (as bitartrate) 1: 200, 000 for injection via local infiltration, peripheral nerve block, and caudal and lumbar epidural blocks. Solutions of Bupivacaine Hydrochloride may be autoclaved if they do not contain epinephrine. Solutions are clear and colorless.


Bupivacaine Hydrochloride Applications:


Bupivacaine hydrochloride is prescribed for caudal, epidural, peripheral, or sympathetic anesthetic block.On the other hand, bupivacaine hydrochloride is also a local anaesthetic of the amide type used in eye surgery. It is used in 0.25-0.75% solution and often mixed with lidocaine hydrochloride.Moreover, its action starts after about 5 minutes and lasts for about 10 hours.

Bupivacaine hydrochloride has many other effects.For example, it is a local anesthetic used for peripheral nerve block, infiltration, and sympathetic, caudal or epidural block.


Bupivacaine Hydrochloride COA:


Test Items Specification Test Results
Appearance Fine, white, crystalline, odorless powder confirm
Identification ABC in Pass confirm
Solubility Free soluble in water and in alcohol; slightly soluble in chloroform and in acetone confirm
Melting point Melts at about 248 degree with decomposition confirm
PH 4.5_6.0 5.16
Related substance Not more than the reference solution 1.0% 0.40%
Heavy metals ≤ 0.001% < 0.001%
Residue on ignition ≤ 0.10% 0.047%
Water 4.0_6.0% 5.0%
Residual Solvents Alcohol ≤ 2.0%
Isopropylic alcohol ≤ 2.0%
Not detect
Assay More Than 98.5 % 99.51%
Conclusion Confirms USP 32
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