Orlistat (Xenical) Powder (96829-58-2)
Product Name: Orlistat
Synonyms:(-)-Tetrahydrolipstatin(EquivalentToOrlistat);Orlipastat
CAS: 96829-58-2
MF:C29H53NO5
MW:495.73
Appearance: White crystalline powder
Purity: 99.51%
Standard:USP
Use:An antiobesity agent. A pancreatic lipase inhibitor. Antiobesity agent. Orlistat is an pancreatic lipase inhibitor. Tetrahydrolipstatin (orlistat) is a semi-synthetic derivative of lipstatin, a metabolite isolated from Streptomyces toxytricini. Tetrahydrolipstatin is widely used for the treatment of obesity.
Orlistat Description:
Orlistat (also known as tetrahydrolipstatin) is a drug designed to treat obesity. In most countries, it is sold under the trade name of Roche as a prescription drug and sold by GlaxoSmithKline in the UK and the United States. Its main function is to prevent the intake of fat in the body’s diet as a lipase inhibitor, thereby reducing calorie intake. It applies to low-calorie diets that health care providers supervise.
Orlistat Application:
The effectiveness of orlistat in promoting weight loss is clear, albeit moderately. The pooled data from clinical trials show that people who give olivide have less than 2-3 kilograms (4.4-6.6 pounds) of medication than a year, except for changes in lifestyle such as diet and exercise. Is also a modest reduction in blood pressure, it seems to be able to prevent the onset of type 2 diabetes, whether due to weight loss itself or other effects; in a large randomized controlled trial, orlistat he was found in obese people will reduce the incidence of diabetes by nearly 40%.
Orlistat Dosage:
1) Usual Adult Dose for Obesity:
120 mg orally three times a day with each main meal containing fat. The dose may be taken during the meal or within 1 hour of completing the meal.
Your daily intake of fat, carbohydrate and protein should be distributed over three meals. This means you will usually take one capsule at breakfast, one at lunch and another at dinner. To gain optimal benefit, avoid the intake of food containing fat between meals, such as biscuits, chocolate and savory snacks.
2) Usual Pediatric Dose for Obesity:
12 years or older:120 mg orally three times a day with each main meal containing fat.
The dose may be taken during the meal or within 1 hour of completing the meal.
Orlistat COA:
| Items |
Standard |
Results |
| Description |
White to kind of white powder |
kind of white powder |
| Melting point |
193.0-200 |
196.0-198.9 |
| Water |
5-6.5% |
5.6% |
| Solubility |
Soluble in methanol |
Complies |
| PH |
4.0-6.0 |
5 |
| Heavy Metals |
<10ppm |
Complies |
| Assay |
>96% |
99.2% |
| Residue on ignition |
<0.1% |
0.03% |
| Single impurity |
<0.2% |
0.19% |
| Conclusion |
Up to the Standard USP 32. |
Rowe Chen
Sales Manager