Arimidex (Anastrozole) Powder (120511-73-1)
- Anastrozole
- Alias: Anastrozole,Arimidex,Armotraz,Anastrol,Egistrozol,Anastrozolo
- Purity : 99%min
- CAS Registry Number: 120511-73-1
- Einecs No: 233-894-8
- Molecular formula: C17H19N5
- Molecular weight:293.37
- Grade : Pharmaceutical Grade
- Storage: Shading, confined preservation
- Usage : pharmaceutical material, etc
Arimidex (Anastrozole) Description:
1 . Anastrozole (INN) ( Arimidex ) is a non-steroidal aromatase-inhibiting drug approved for treatment of breast cancer after surgery, as well as for metastasis in both pre and post-menopausal women. The severity of breast cancer can be increased by estrogen, as sex hormones cause hyperplasia, and differentiation at estrogen receptor sites.Anastrozole works by inhibiting the synthesis of estrogen. This medication is used to treat breast cancer in women who have gone through “the change of life” (menopause). Anastrozole works by lowering estrogen hormone levels to help shrink tumors and slow their growth.
2 . The drug is appropriately used when using substantial amounts of aromatizing steroids, or when one is prone to gynecomastia and using moderate amounts of such steroids. Arimidex does not have the side effects of aminoglutethimide (Cytadren) and can achieve a high degree of estrogen blockade, much moreso than Cytadren. It is possible to reduce estrogen too much with Arimidex, and for this reason blood tests, or less preferably salivary tests, should be taken after the first week of use to determine if the dosing is correct.
3 . Anastrozole (arimidex) is an extremely powerful anti-estrogen officially belonging to the Aromatase Inhibitor (AI) family under the trade name Arimidex, this is perhaps the most commonly used AI and one of the most common anti-estrogens on the market. Arimidex has proven to be very effective in breast cancer treatment, even more so than traditional Nolvadex (Tamoxifen Citrate), and is a favorite anti-estrogen among many anabolic steroid users. Countless anabolic steroid users rely on Arimidex for on cycle estrogenic protection. Many anabolic steroids have the ability to aromatase and lead to excess estrogen,which in turn can lead to some of the most commonly associated side effects of anabolic steroid use.
Arimidex (Anastrozole) Applications:
The drug is appropriately used when using substantial amounts of aromatizing steroids, or when one is prone to gynecomastia and using moderate amounts of such steroids. Arimidex does not have the side effects of aminoglutethimide (Cytadren) and can achieve a high degree of estrogen blockade, much moreso than Cytadren. It is possible to reduce estrogen too much with Arimidex, and for this reason blood tests, or less preferably salivary tests, should be taken after the first week of use to determine if the dosing is correct.
Arimidex (Anastrozole) COA:
Items |
Standard |
Results |
Description |
White crystalline powder |
Complies |
Identification |
IR
HPLC
Reactive |
Conform with standard IR
Conform with standard HPLC
Conform |
Solubility |
Freely soluble
in methanol,
acetone,ethanol
and tetrahydrofuran.
And very soluble in
acetonitrile |
Complies |
Total Impurity |
max.0.5% |
0.18% |
Total Unspecified Impurity |
max. 0.2% |
0.08% |
Individual unspecified
impurlty |
max. 0.1% |
0.05% |
Related compound B |
max. 0.2% |
0.07% |
Related compound C |
max. 0.2% |
0.04% |
Related compound D |
max. 0.1% |
0.05% |
Related compound E |
max. 0.1% |
0.06% |
Limit of cyclohexane |
max. 0.08% |
ND |
Limit of ethylacetate |
max. 0.1% |
0.07% |
Melting point |
81.0~84.0ºC |
82.5~83.2ºC |
Water |
max. 0.3% |
0.21% |
Residue on ignition |
max. 0.1% |
0.07% |
Heavy Metals |
max.0.001% |
Complies |
Assay(HPLC) |
98.0%~102.0% |
99.8% |
Storage |
Cool and dry |
|
Conclusion |
It complies to USP32 . |
Arimidex (Anastrozole) Dosage:
Dosages of arimidex will vary from person to person. This is why blood work is essential to finding the perfect balance. One should start out at half a mg every other day and adjust as needed for the cycle. Some AAS users will not use an AI at first but they will have it on hand just in case. This isn’t always a good idea, as once you start noticing gyno or excessive water weight it could be too late to reverse. Since AAS will continue building in the body and aromatize (steroids turning into estrogen), taking arimidex at this point would be like trying to stop a car already in motion.
For men: 0.5mgs per day or every other day. Remember, it’s steroid dose dependent.