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7-Keto-Dehydroepiandrosterone (7-keto DHEA) Powder CAS 566-19-8


Product name 7-Keto-DHEA
Other name 7-Oxodehydroepiandrosterone; 7-Ketodehydroepiandrosterone; 7-Keto-DHEA; 7-Oxo-DHEA; DHEA, 7-keto-; UNII-2334LJD2E9; 3beta-Hydroxyandrost-5-ene-7,17-dione; (3beta)-3-hydroxyandrost-5-ene-7,17-dione; 7-Ketodhea; 7-keto DHEA; 7-KETO-DHEA; 7-Keto-Dehydroepiandrosterone
CAS 566-19-8
Boiling poin 477.1°C at 760 mmHg
MF C19H26O3
MW 302.4079
Molecular Structure 7-Keto-DHEA
Purity 99%
Appearance white crystalline powder


7-keto-DHEA Descriptions:


The World Anti-Doping Agency lists 7-keto DHEA as a prohibited anabolic agent.

While in vitro and animal studies have suggested potential uses for 7-Keto in humans, there is currently limited scientific evidence to support its use as a weight-loss aid, muscle-builder, immune stimulant, or for any other clinical use.

One randomized, placebo-controlled research study on dieting and exercising healthy overweight individuals found 7-keto significantly increased body-weight loss and fat-loss.

7-Keto is marketed as a dietary supplement with the implication that it may accelerate weight loss, increase metabolism, enhance memory, or prevent age-related changes. When used in a topical (skin lotion) product 7-Keto caused long-lasting changes in the body’s levels of testosterone, epitestosterone, estradiol, and other steroid hormones.

Researchers have raised concern that supplements may trigger positive tests for performance-enhancing drugs.


7-keto-DHEA Applications:


7-Keto-DHEA is unique among other derivatives of DHEA because of its oxygenated 7-position. This molecular configuration imparts different characteristics to the molecule, and research reveals that 7-Keto DHEA has multiple distinct effects in the body.


7-keto-DHEA Benefits:


Increased metabolism/weight loss:


7-Keto demonstrates documented thermogenic activity in rats. This is accomplished through the activation of three thermogenic enzymes: Glycerol-3-Phosphate Dehydrogenase, Malic Enzyme and Fatty Acyl CoA Oxidase.

In keeping with the biological definition of thermogenesis, all three of these enzyme activations drive energy-producing substrates in a direction of less efficient ATP production relative to heat production. The enzymes also promote the utilization of fat stores for energy and heat production. This is the basis for 7-Keto’s ability to enhance thermogenesis and, through that mechanism, accelerate the utilization of fat stores for energy.


Age-related immune enhancement:


Although the aging process affects all of the segments of the immune system, investigators have identified abnormalities in the cellular or T-cell mediated immune function in the elderly. The decline in T-cell immune function is associated with an increased susceptibility to infections.

For example, individuals with age-related declines in cellular immunity have an impaired response to influenza vaccine, making them more susceptible to getting the “flu” even though they have had their flu shot.

In a clinical study presented at the Federation of American Societies for Experimental Biology meeting in April 2004, the effect of 7-Keto was evaluated in regard to its effect on elderly immune function.


7-keto-DHEA COA:


Test Specification Results
Characteristics White to almost white crystalline powder conforms
Melting point 240.0~ 244.0℃ 241.9~243.1℃
Heavy metal ≤10ppm 10ppm
Residue on ignition ≤0.1% 0.05%
Loss on drying ≤0.5% 0.05%
Assay 97.0 ~ 103.0% 99.24%
Particle size 100%≤20um Pass
T.L.C Only one spot Pass
Conclusion This batch complies with Enterprise Standard.
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