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    1-Testosterone Base Powder (65-06-5)

     

    Product Name:1-Testosterone
    Alias:(5alpha,17beta)-17-Hydroxyandrost-1-en-3-one; 17beta-Hydroxy-5alpha-androst-1-en-3-one; 5.alpha.-Androst-1-en-3-one, 17.beta.-hydroxy-; Androst-1-en-3-one, 17-hydroxy-, (5.alpha.,17.beta.)-; androst-1-en-3-one, 17-hydroxy-, (5alpha,17beta)-
    MF:C19H28O2
    MW:288.4244
    CAS:65-06-5
    Boiling point:420.5°C at 760 mmHg
    Appearance:White Crystalline Powder

     

    1-Testosterone Description:

     

    1-Testosterone has a structure similar to testosterone but the double bond is in a different place. 1-Testosterone is a 1,2-double bond instead of a 4,5-double bond in its A ring. This slight modification means that the molecule is subject to different metabolism than standard testosterone. It cannot be converted to estrogen via aromatase nor can it be turned into DHT. This makes it a very stable molecule and resists most traditional routes of metabolism. A 2006 study determined that 1-testosterone has a high androgenic and anabolic potency even without being metabolized. 1-testosterone binds in a manner that is highly selective to the androgen receptor (AR) and has a high potency to stimulate AR-dependent transactivation. 1-Testosterone has an anabolic to androgenic ratio of 200/100, which is superior to testosterone!

    1-Testosterone is also known as dihydroboldenone and 1-dehydroandrostanolone. It may be listed under the nomenclatures 17b-hydroxy-5a-androst-1-en-3-one and 5a-androst-1-en-3-one, 17b-ol. 1-Testosterone is the 5a reduced form of boldenone (Equipoise). 1-Testosterone was the first fully active steroid introduced to the dietary supplement market.

    1-Testosterone has an anabolic to androgenic ratio of 200/100. With 1-testosterone, many users report a hardening effect and an increase in vascularity. 1-testosterone appears to be best used for size gains, although it should still provide the user with strength gains as well. In effect, 1-testosterone has been compared to Primobolan and Equipoise, though overall it is a much more potent compound mg for mg. 1-testosterone is considered a “dry” compound which can be used during cutting phases yet because of its strength is can also be useful during a bulking phase.

    With its favorable anabolic to androgenic ratio, the low doses needed to see results, and the fact that 1-testosterone is already 5a reduced, androgenic side effects should not be too high with this compound in comparison to other steroids like testosterone. 1-testosterone cannot convert to estrogen, so the user should not experience bloating while on cycle and the risk of developing gynecomastia is low when 1-testosterone is used alone. One side effect commonly experienced by 1-testosterone users is lethargy. The exact reason for this lethargy is unknown, but it may be due to the fact that 1-testosterone lacks the energy and libido boosting effects of testosterone yet is still suppressive of natural testosterone production, or because of low estrogen levels. Stacking 1-testosterone with a more androgenic compound during a cut or a “wet” compound during a bulk does appear to relieve the issue of lethargy in most users.

    Orally, 1-testosterone hes a very short half-life and is not very bioavailable because it is not methylated to avoid breakdown by the liver. When 1-testosterone is administered as a transdermal (absorbed through the skin), bioavailability is increased but its short half-life is still an issue. 1-testosterone was also sold as an injectable as 1-testosterone cypionate, which greatly increased half-life to about 4-5 days, making this the most effective way to use 1-testosterone. When injected, only 100-200mg/week is needed for an effective cycle.

     

    1-Testosterone Applications:

     

    1-Testosterone would give you clean gains that are very dry and lean in nature. This means you won’t get a lot of bloat or estrogen activity with this prohormone. The lack of estrogen actually causes most people to stack this steroid with 4-andro or another “wet” compound. This helps potentiate the gains and increase the “comfort” of the cycle. 1-Testosterone will help give you clean gains that are very sustainable and help your strength go through the roof .

    With 1-Testosterone, many users report a hardening effect and an increase in vascularity. 1-Testosterone appears to be best used for size gains, although it provides the user with incredible strength gains as well. 1-Testosterone is considered a “dry” compound which can be used during cutting phases yet because of its strength is can also be useful during a bulking phase.

    Bodybuilders, fitness enthusiasts, and athletes pay attention. The muscle-building breakthrough of the 21st century is here and the results being achieved by 1-Testosterone has been phenomenal. 1-Testosterone works to create the perfect anabolic environment for unbelievable gains in lean muscle mass and strength that will not disappear when your cycle is completed!

     

    1-Testosterone Benefits:

     

    Dihydroboldenone, while not overly androgenic, is a potent anabolic. It has been demonstrated that the drug binds extremely well and selectively to the androgen receptor and stimulates androgen receptor transactivation of dependent reporter genes . This equates to a drug that possesses the ability to stimulate significant muscle growth while not producing androgenic side effects.Also it does not aromatize and therefore estrogenic side effects such as gynecomastia and water retention are not a concern for users. It has been shown to be by far more anabolic than such compounds as boldenone, nandrolone , and even testosterone itself. Obviously this is of great benefit to many athletes.

     

    1-Testosterone Use/Dosing:

     

    As for specific dosages used with this drug, the low end is primarily thought to be 300-400mg a week for male users. For females the usual rules apply with dihydroboldenone as they do with other drugs. Anywhere from 25-100mg per week would be a good starting point for the majority of female users who have little to moderate experience with anabolic drugs.

    The frequency of dosing with dihydroboldenone depends on the ester used with the compound. Seemingly the most popular current ester to produce the drug with is cypionate. Typcially, males would use a dosage of 200-400mg Dihydroboldenone Cypionate a week.No matter what ester utilized however the same rules would apply as with any other drug in terms of the frequency of administration needed to maintain relatively stable blood levels of the compound.

    Orally, 1-testosterone has a very short half-life and is not very bioavailable because it is not methylated to avoid breakdown by the liver. When 1-testosterone is administered as a transdermal (absorbed through the skin), bioavailability is increased but its short half-life is still an issue. 1-testosterone was also sold as an injectable as 1-testosterone cypionate, which greatly increased half-life to about 4-5 days, making this the most effective way to use 1-testosterone. When injected, only 100-200mg/week is needed for an effective cycle.

     

    1-Testosterone Risks/Side Effects:

     

    With the positive aspects of the lack of aromatization associated with dihydroboldenone also come the negative ones. Fortunately these are primarily limited to such symptoms as lethargy, malaise and possibly a reduction in sex drive. These are caused by a lower ratio of estrogen in comparison to androgens in the body. For the most part however this effect is relatively slight and can be avoided with the use of steroids that do aromatize in conjunction with dihydroboldenone and thus restore a better balance in terms of androgens versus estrogen.

    It also appears that the administration of dihydroboldenone may result in an increase in liver weight . This effect occurred when administering the drug orally but should also be true of the drug when administered via intramuscular injection. There is no research to indicate this however.

    Other common negative side effects associated with the use of anabolic/androgenic steroids are still relatively mild with the use of dihydroboldenone. Of course suppression of the natural testosterone production of users will occur like with all steroids, however other side effects such as an increase in blood pressure, acne and others are comparably mild and often times non-existent in users, at least as they are directly related to the administration of this drug.

    In terms of side effects for women, at moderate to heavy doses symptoms of virilization are likely. These can include such symptoms as clitoral enlargement, body hair growth and deepening of the voice. At lower doses however these side effects should not be a concern for the majority of potential female users.

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