Prilocaine (Prilocaine Base) Powder CAS 721-50-6
Product Name:Prilocaine
Synonym:astra1512;astra1515;Citanest;L 67;l67;n-(2-methylphenyl)-2-(propylamino)-propanamid;o-Methyl-2-propylaminopropionanilide;o-Methyl-alpha-propylaminopropionanilide
CAS:721-50-6
MF:C13H20N2O
MW:220.31
EINECS
211-957-0
Appearance:White Crystalline Powder
Melting Point:37-38°
Boiling Point:bp0.1 159-162°
Grade:Pharma Grade
Usage:Local anesthetic; Mainly used in mucosa anesthetic
Prilocaine Description:
Prilocaine is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Löfgren. In its injectable form (trade name Citanest), it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used for intravenous regional anaesthesia (IVRA).
Prilocaine Applications:
Prilocaine topical is a local anesthetic (numbing medication). It works by blocking nerve signals in your body. Prilocaine topical is used to numb the skin, or surfaces of the penis or vagina, in preparation for a medical procedure or to lessen the pain of inserting a medical instrument such as a tube or speculum.
Proparacaine hydrochloride and tetracaine are also indicated to produce local anesthesia prior to surgical procedures such as cataract extraction and pterygium excision, usually as an adjunct to locally injected anesthetics.
Ophthalmic solutions used for intraocular procedures should be preservative-free. Preservatives may cause damage to the corneal epithelium if a significant quantity of solutionenters the eye through the incision.
Prilocaine COA:
| Items |
Specification |
Results |
| Description |
White crystalline powder |
Complies |
| Solubility |
Freely soluble in water and in alcohol,slightly soluble in chloroform, very slightly soluble in acetone, practically insoluble in ether |
Complies |
| Identification |
Should be positive response |
Complies |
| Melting Point |
166~169ºC |
166~168ºC |
| Loss on drying |
≤ 0.3% |
0.13% |
| Residue on ignition |
≤0.1% |
0.03% |
| Heavy metals |
≤0.002% |
<0.002% |
| Residual solvents |
Should comply with the standard |
Complies |
| Assay |
99.0% ~101.0%(on dried basis) |
99.46% |
| Conclusion |
Qualified |
Rowe Chen
Sales Manager