Organic Solvents Pharmaceutical Raw Materials 1.4-Butanediol / BDO For Cosmetics 110-63-4

1,4-Butanediol Info:

Name: 1,4-Butanediol
Synonyms:1,4-Butylene Glycol;1,4-Butanediol;1,4-Dihydroxybutane;Butanediol, 1,4-;Tetramethylene Glycol;Versalink Curative 1,4 Bdo
:110-63-4
MF:C4H10O2
MW:90.12
EINECS:203-786-5
Chemical Properties:
mp 20 °C
bp 230 °C(lit.)
density 1.017 g/mL at 25 °C(lit.)
vapor density 3.1 (vs air)
refractive index n20/D 1.445(lit.)
Fp 135 °C
storage temp. 2-8°C
Water Solubility Miscible
Sensitive Hygroscopic
BRN 1633445
Stability: Stable. Combustible. Incompatible with strong oxidizing agents, mineral acids, acid chlorides, acid anhydrides.
Safety Information:
Hazard Codes Xn
Risk Statements 22-67
Safety Statements 36-23
WGK Germany 1
RTECS EK0525000
HS Code 29053980

General Description: Odorless colorless liquid or solid (depending upon temperature).
Usage:1,4-Butanediol is used in the synthesis of epothilones, a new class of cancer drugs. Also used in the stereoselective synthesis of (-)-Brevisamide.
Air & Water Reactions:Highly flammable. 1,4-Butanediol is hygroscopic. Water soluble.
Reactivity Profile:1,4-Butanediol is heat and light sensitive. 1,4-Butanediol reacts with acid chlorides, acid anhydrides and chloroformates. 1,4-Butanediol also reacts with oxidizing agents and reducing agents. 1,4-Butanediol is incompatible with isocyanates and acids. 1,4-Butanediol is also incompatible with peroxides, perchloric acid, sulfuric acid, hypochlorous acid, nitric acid, caustics, acetaldehyde, nitrogen peroxide and chlorine.
Health Hazard:Ingestion of large amounts needed to produce any symptoms.

Description:

BDO is the short name of 1,4-Butanediol, it is a kind of colorless viscous oil-like liquid, combustible and can mixing with water. With freezing point of 20.1 Degree C, boiling point of 228 Degree C,171 Degree C(13.3kPa),120 Degree C(1.33kPa),86 Degree C(0.133kPa, the relative density of 1.0171(20/4 Degree C). The index of refraction is 1.461, flash point is 121 Degree C. It can soluble in methanol and ethanol, slightly soluble in ether. It has bitter taste and moisture absorption.

Legality of 1,4-Butanediol:

While 1,4-butanediol is not currently scheduled federally in the United States, a number of states have classified 1,4-butanediol as a controlled substance. Individuals have been prosecuted for 1,4-butanediol under the Federal Analog . A federal e in New York in 2002 ruled, but that decision was later overturned by the Second Circuit. However, a Federal District Court in Chicago ruled, and the Seventh Circuit Court of Appeals upheld that ruling. In the United Kingdom, 1,4-butanediol was scheduled in December 2009 as a Class C controlled substance. In Germany, the drug is not explicitly illegal, but might also be treated as illegal if used as a drug. It is controlled as a Schedule VI precursor in Canada.

Industrial Use of 1,4-Butanediol:

1,4-Butanediol is used industrially as a solvent and in the manufacture of some types of plastics, elastic fibers and polyurethanes. In organic chemistry. In the presence of phosphoric acid and high temperature, it dehydrates to the important solvent tetrahydrofuran. At about 200 °C in the presence of soluble ruthenium catalysts, the diol undergoes dehydrogenation to form butyrolactone.

World production of 1,4-butanediol was claimed to be about one million metric tons per year and market price is about 2,000 USD (1,600 EUR) per ton (2005). In 2013, worldwide production was claimed to be billions of lbs (consistent with approximately one million metric tons).

Usage:

1.1,4 butanediol is an important raw materials for organic and refined. It is the basic material for producing PBT plastics and fiber, and PBT is one of the five most promising engineering plastics.

2. 1,4butanediol is the main raw material for producing THF, which is an important organic solvent. The polymeric compound PTMEG of THF forms the basic material for highly-elastic urethane elastic fiber, which is mainly used for producing high-grade sports wear and swimming suit that requir high elasticity.

3. 1,4-butanediol is the main material for producing γ-butyrolacton, which is widely used in pesticide, pharmaceuticals, cosmetics and other industries due to its ability to produce 2-pyrrolidone, NMP and their derivatives NVP and PVP etc. high add-ons products.

4. 1,4butanediol is the main material for producing polyurethane artificial leather, polyurethane, elastomer and polyurethane sole glue. polyurethane elastomer are widely used to manufacture elastic sole, auto solid fire, friction conveying belt and etc.