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Pharmaceutical Chemicals

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Lorcaserin Hydrochloride Hemihydrate Powder (856681-05-5)

 

Product Name:Lorcaserin hydrochloride hemihydrate
Synonyms:Lorcaserin HCl 0.5H2O; R-Lorcaserin hydrochloride hemehydrate; Lorcaserin HCl Hemihydrate; Belviq; (1R)-8-Chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine hydrochloride hemihydrate; (1R)-8-Chloro-2,3,4,5-tetrahy dro-1-methyl-1H-3-benzazepine Hydrochloride.1/2H2O
CAS:856681-05-5
MF:2(C11H14ClN).2(HCl).H2O
MW:579.39
Appearance: White powder
Purity: 99.75%
Melting point: 198-202°C
Usage: Lorcaserin hydrochloride is a serotonin 2C receptor agonist for oral administration used for chronic weight management.

 

Lorcaserin Hydrochloride Hemihydrate Descriptions:

 

Lorcaserin Hydrochloride (Belviq) is an FDA-approved prescription weight-loss medication that, when used with diet and exercise, can help some overweight adults with a weight-related medical problem, or obese adults, lose weight and keep it off. It is not known if BELVIQ when taken with other prescription, over-the-counter, or herbal weight loss products is safe and effective. It is not known if BELVIQ changes your risk of heart problems, stroke, or death due to heart problems or stroke.

 

Lorcaserin Hydrochloride Hemihydrate Applications:

 

Lorcaserin Hydrochloride is an FDA-approved prescription weight-loss medication that, when used with diet and exercise, can help some overweight adults with a weight-related medical problem, or obese adults, lose weight and keep it off.

Lorcaserin Hydrochloride is a serotonin 2C receptor agonist. It has been shown to decrease food consumption and promote satiety by selectively activating serotonin 2C receptors in the brain.

Lorcaserin Hydrochloride is specifically indicated as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in clinically obese adults (BMI of 30 kg/m2 or greater) and overweight adults (BMI of 27 kg/m2 orgreater) with at least one weight-related comorbid condition.

Lorcaserin Hydrochloride is supplied as a tablet designed for oral administration. The recommended dose is one 10mg tablet twice daily. Use of Lorcaserin Hydrochloride should be discontinued if 5%weight loss is not achieved by week 12 of treatment.

 

Lorcaserin Hydrochloride Hemihydrate COA:

 

Appearance white to off-white powder White powder
Identification HNMR/HPLC spectrum/Thermogravimetric Analysis Conform
Peaks(2θ) 13.7°,14.9°,15.4°,15.8°, 13.7°,14.89°,15.4°,
Assay 98.0%-102.0% 99.8%
Enantiomer ≤1% 0.695%
Related Substances Total impurities ≤0.5% 0.02%
Related Substances Single max unknown impurity 0.014%
Dichloromethane ≤0.05% Undetected
Acetone ≤0.5% Undetected
Ethyl acetat ≤0.5% 0.03%
Melting Point 198ºC-202ºC 198.1ºC-199.1ºC
Waters 3.0%-4.5% 3.7%
Residue on Ignition ≤0.1% 0.04%
Heavy Mental ≤20ppm conform
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