China Reliable Steroid Powder Supplier - Dewael Biotech
EnglishالعربيةNederlandsFrançaisDeutschΕλληνικάहिन्दी; हिंदीItalianoPolskiPortuguêsРусскийEspañolภาษาไทยTürkçeУкраїнська

Local Anesthesia Powders

» Pharmaceutical Chemicals » Local Anesthesia Powders

  • Specifications

 

Levobupivacaine Hydrochloride (Levobupivacaine HCL) Powder CAS 27262-48-2

 

Product Name Levobupivacaine hydrochloride
CAS 27262-48-2
MF C18H29ClN2O
MW 324.89
Purity 99%
Appearance white crystalline powder
Usage Local anaesthetics
Categories Pharmaceutical Raw Materials;Active Pharmaceutical Ingredients;API;Inhibitors
Synonyms TIMTEC-BB SBB001337;(S)-(-)-BUPIVACAINE HCL;
(S)-(-)-BUPIVACAINE HYDROCHLORIDE;
(S)-(-)-1-N-BUTYL-2′,6′-DIMETHYL-2-PIPERIDINCARBOXANILID HYDROCHLORIDE; (S)-(-)-1-BUTYL-2-(2,6-XYLYLCARBAMOYL)-PIPERIDINE HYDROCHLORIDE; s-(-)-1-butyl-2′,6′-pipecoloxylidide hydrochloride; (s)-1-butyl-2′,6′-piperidinecarboxamidemonohydrochloride; (s)-1-butyl-n-(2,6-dimethylphenyl)-2-piperidinecarboxamidemonohydrochloride

 

Levobupivacaine Hydrochloride Description:

Levobupivacaine (rINN) is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine.It is the hydrochloride salt of levobupivacaine, an amide derivative with anesthetic property.

Levobupivacaine reversibly binds voltage-gated sodium channels to modulate ionic flux and prevent the initiation and transmission of nerve impulses (stabilizing neuronal membrane), thereby resulting in analgesia and anesthesia. In comparison with racemic bupivacaine, levobupivacaine is associated with less vasodilation and has a longer duration of action.

Levobupivacaine hydrochloride is a sodium channel blocker used as a long-acting local anaesthetic for epidural anesthesia. Levobupivacaine is the isomer of bupivacaine, with efficacy similar to that of bupivacaine with a reduced risk of cardiotoxicity.

 

Levobupivacaine Hydrochloride Application:

 

Levobupivacaine is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by Abbott under the trade name Chirocaine. Bupivacaine is an amide-type local anaesthetic. Although it blocks neuro transmission, its membrane stabilising action also affects the myocardium. This can cause fatal cardiotoxicity. As bupivacaine is widely used in surgery and obstetrics, attempts have been made to develop a safer long-acting local anaesthetic.

The bupivacaine molecule is a racemic compound. Levobupivacaine is the S-enantiomer of bupivacaine and is thought to have less cardiotoxic potential than the R-enantiomer. The pharmacokinetic parameters of levobupivacaine are similar to those of bupivacaine.

Levobupivacaine has been studied in surgical anaesthesia and for pain management. It can be used for local infiltration, epidural, intrathecal and peripheral nerve blocks. For epidural analgesia it can be given with clonidine. Double-blind comparisons of levobupivacaine and bupivacaine show that their anaesthetic effects are similar.

 

Levobupivacaine Hydrochloride Dosage and Usage:

 

Indications are mainly used for surgical epidural anesthesia.Adult for nerve block or infiltration anesthesia, a maximum dose of 150mg. Concentration of the preparation of the solution: surgical epidural block: 0.5% ~ 0.75% 10 ~ 20ml 50 ~ 150mg moderate to all motor block.

 

Levobupivacaine hydrochloride COA:

 

Test Items Specification Test Results
Description White or almost white crystalline powder White crystalline powder
Melting Point 191.0~193.0ºC 192ºC
Loss of drying ≤1.0% 0.5%
Heavy Metal ≤20ppm 15ppm
TLC Only one spot Only one spot
Assay ≥99.5% 99.91%
Conclusion It complies with the USP 32.
Share With Friends

Enquiry Form ( we will get back you as soon as possible )

Name:
*
Email:
*
Message:

Verification:
0 + 7 = ?

Maybe you like also

  • Product Categories

  • Share With Friends

  • Customer Reviews

    Customer Service was excellent , very fast shipping! Very pleased with this company and their products! Thanks

    — Mr. Mack

     

    best supplier i’ve met, always high purity with smart packing

    — Mr.Steve

     

    super! spend more than 6 orders, quality products, fast delivery, perfect communication, perfect team I recommend thank you

    — Mr. Luis

     

    Great company to deal with.High quality products.
    Yes it did come thru in Australia. No problems. Will deal with dewael again for sure. Thanks so much.
    — Mr. Jeff

     

    I have ordered testo that is of good quality and cheap price. Fast delivery of products without problems. Very good customer serve, they are mi best friends and the factory is the TOP. Reccomndable.

    —John

  • Contact Us

    URL:www.steroid-sarms.com

    Email:Rowe@steroid-sarms.com

    Cerina@steroid-sarms.com

    Address:North Baiyun Ave.,Baiyun,Guangzhou,China

  • BTC LIVE PRICES