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Estradiol Powder Series

» Steroid Raw Powders » Estradiol Powder Series

  • Specifications

Raw Estradiol Cypionate powder basic Characters:

 

Name: Estradiol Cypionate
CAS: 313-06-4
Molecular Formula: C26H36O3
Molecular Weight: 396.56
Melt Point: 300°C
Storage Temp: RT
Color: White or off white crystalline powder

 

Description:

Estradiol cypionate (brand names Depo-Estradiol, Depofemin, Estradep, and many others), or estradiol cipionate, also known as estradiol 3-cyclopentylpropionate, is a synthetic estrogen ester, specifically the 3-cyclopentylpropanoyl ester, of the natural estrogen estradiol. It was first introduced in 1952 by Upjohn in the United States, and has been in widespread use since. Estradiol cypionate behaves as a sustained-release prodrug to estradiol, and therefore is considered to be natural estrogen.

Estradiol cypionate is absorbed more slowly than estradiol itself, and for that reason, can be administered less often. Compared to other commonly used estradiol esters, via the intramuscular route, estradiol cypionate was found to have the longest duration of action with a duration of ~11 days, while estradiol benzoate and estradiol valerate were found to last for 4–5 days and 7–8 days, respectively. Estradiol cypionate, as a depot injection, has been found to have equivalent effectiveness and pharmacokinetics (e.g., duration) via subcutaneous and intramuscular routes. However, subcutaneous injection is generally regarded as easier and less painful relative to intramuscular injection, and for these reasons, may result in comparatively greater patient compliance.

Lunelle and Cyclofem are combination formulations of 4 mg estradiol cypionate and 25 mg medroxyprogesterone acetate for intramuscular use as long-lasting (once-monthly) contraceptives. With these formulations, estradiol levels peak 2 days post-administration at mean serum levels of 247 pg/mL. The terminal half-life of estradiol with these formulations is approximately 8 days, and plasma estradiol levels return to baseline (typically about 100 pg/mL) by 14 days post-administration. At 28 days post-administration, estradiol levels reach a low of 40 to 55 pg/mL.

 

Raw Estradiol Cypionate powder usage

1. Names:

Estradiol Cypionate is also know as EC, E2C, Depo-Estradiol, Depofemin, Estradep, etc.

 

2.Raw Estradiol Cypionate powder Usage:

Lower dosage formulations of 1 mg/mL and 3 mg/mL were also previously marketed.

 

3. Warning on Raw Estradiol Cypionate powder:

The Women’s Health Initiative (WHI) study reported increased risks of myocardial infarction, stroke, invasive breast cancer, pulmonary emboli, and deep vein thrombosis in postmenopausal women (50 to 79 years of age).

 

4.Further instructions:

Estradiol cypionate is usually handled and stored by a health care provider. If you are using estradiol cypionate at home, store estradiol cypionate as directed by your pharmacist or health care provider. Keep estradiol cypionate out of the reach of children and away from pets.

 

5. Estradiol Cypionate Raw Powder:

Min order 10grams.
The inquiry on normal quantity(Within 1kg) can be sent out in 12 hours after payment.
For larger order(Within 1kg)can be sent out in 3 workingdays after payment.

 

6. Estradiol Cypionate Raw Powder Recipes:

To inquiry our Customer Representitive(CSR) for details, for your reference.

 

7. Raw Estradiol Cypionate powder Marketing:

To be provided in the coming future.

 

Estradiol Cypionate Usage:

Estradiol cypionate (Depo-Estradiol, Depofemin, Estradep, many others), or estradiol cipionate, is a synthetic ester, specifically the 3-cyclopentylpropanoyl ester, of the natural estrogen, estradiol. It was first introduced in 1952 by Upjohn in the United States, and has been in widespread use since. Estradiol cypionate is absorbed more slowly than estradiol itself, and for that reason, it can be administered less often. Compared to other commonly used estradiol esters, via the intramuscular route, estradiol cypionate was found to have the longest duration of action with a duration of ~11 days, while estradiol benzoate and estradiol valerate were found to last for 4-5 days and 7-8 days, respectively.

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